Turn protein dynamics into a premium service.
CROs that offer EPR-based structural analysis win mandates that competitors can't touch. FATHOM™ makes it operationally and economically viable for the first time.
Structure isn't static.
Cryo-EM, NMR, AlphaFold, and X-ray crystallography give you a snapshot. Biological function lives in what the snapshot misses — the loops that flex, the domains that switch, the conformational ensembles that decide how a molecule binds.
Measure the motion.
FATHOM resolves nanoscale distance distributions and conformational dynamics on micromolar samples, in under a few hours, on an instrument built for the structural biology lab.
The world's first quantum-enabled EPR spectrometer.
FATHOM measures the protein dynamics that static structural techniques can't resolve — the conformational motion behind binding, signalling, and drug action.
Built for throughput. Designed for your team.
Previous generations of EPR instruments weren't built for a CRO environment — they required specialized expertise, long acquisition times, and handled samples one at a time. FATHOM was designed differently.
Superconducting Quantum Sensing
New superconducting quantum-sensing resonator design enables accessible scientific discoveries and higher throughput than classical EPR.
Short Acquisition Times
Increase in sensitivity, speed and stability reduces EPR acquisition time from weeks to days.
New service lines. Differentiated capabilities. Higher-value contracts.
Add EPR-based protein dynamics analysis to your service portfolio and open doors to mandates that require structural insights beyond standard biophysics panels.
GPCR Conformational Profiling
Over 30% of FDA-approved drugs target GPCRs. EPR reveals subtle ligand-induced conformational changes that define agonist, antagonist, and biased signaling behavior — data your pharma clients need and can't easily get elsewhere.
Cryo-EM & AlphaFold Validation
Cryo-EM time is expensive and competitive. Help clients maximize it. EPR provides fast, point-to-point distance constraints that screen protein samples and validate structural predictions before clients commit to microscope time.
PROTACs & Targeted Protein Degraders
The efficacy of molecular glues and PROTACs depends on precise ternary complex formation. EPR resolves intermolecular distance distributions and quaternary arrangements — critical data for an area where client investment is surging.
Intrinsically Disordered Proteins
IDPs like amyloid-β and tau are implicated in Alzheimer's and other neurodegenerative diseases. Their dynamic nature makes them invisible to NMR and Cryo-EM. EPR captures the probability distributions that define their behavior.
Ready to see FATHOM in action?
Our applications specialists will walk you through a demo, answer technical questions, and help you assess fit for your specific research program.
High Q in the media.
WATERLOO, ON, June 2, 2026 - High Q Technologies has partnered with Creative Biostructure, a Contract Research Organization, to bring our EPR Sample Measurement Service to a wider audience. Researchers can now access a broad array of structural biology tools which includes quantum-enabled EPR spectroscopy data, providing insights into protein dynamics and conformational behaviour without needing direct access to an instrument . Simply reach out through Creative Biostructure to get started.
Not every lab is ready to bring EPR in-house. We have an answer for that.
Whether you want to run your own instrument or send us your samples, High Q can support where you are in your research today — with a clear path to more.
Own the instrument
Roll FATHOM directly into your existing workflow. No EPR expertise required — automated sample handling, load-and-go operation, and publication-ready results from day one.
Sample Measurement Service
Not ready to commit to an instrument? Ship your samples to High Q's applications lab. Our team handles the measurement and returns detailed reports with publication-quality data — fully customised to your system.