High Q Technologies at Discovery & Development US 2026
October 12–13, 2026
Hilton San Diego Bayfront | San Diego, CA
Drug discovery depends on understanding the complex behavior of biological targets. While traditional approaches provide valuable structural insights, proteins are constantly moving between different conformational states that influence function, binding, and therapeutic potential.
Visit HighQ Technologies at Discovery & Development US 2026 to learn how advanced Electron Paramagnetic Resonance (EPR) spectroscopy helps researchers close the conformation gap by revealing protein dynamics that are often missed by conventional methods.
HighQ's EPR solutions provide insights into conformational changes, molecular interactions, and protein behavior, supporting research in target validation, therapeutic development, and biophysical characterization.
Connect with our team in San Diego to discover how understanding protein dynamics can help accelerate better decisions throughout the drug discovery process.
A protein conformational change is often described as a transition from one structural state to another: open to closed, inactive to active, or apo to ligand-bound. That language is useful for describing structural differences, but it can obscure the physical problem that determines how a protein behaves in solution.
Artificial intelligence has changed the starting point for structural biology. Protein structure prediction tools such as AlphaFold can generate highly accurate structural models for many proteins, including proteins for which experimentally determined structures are unavailable.
Structure-based drug design uses the three-dimensional structure of a target protein to identify functional binding sites and design drug molecules that complement their shape, size, and electrostatic properties. This approach has enabled major advances in medicine, including HIV protease inhibitors, antibiotics, and targeted cancer therapies such as imatinib.
Ready to see FATHOM in action?
Our applications specialists will walk you through a demo, answer technical questions, and help you assess fit for your specific research program.